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R J Kreitman Selected Research

Interleukin-4 Receptors (Interleukin 4 Receptor)

1/2002IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4-Pseudomonas exotoxin fusion protein.
3/2000Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo.

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R J Kreitman Research Topics

Disease

17Neoplasms (Cancer)
01/2022 - 02/2000
5Hematologic Neoplasms (Hematological Malignancy)
12/2001 - 04/2000
3Hairy Cell Leukemia
01/2017 - 02/2000
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2007 - 02/2000
2Glioma (Gliomas)
01/2002 - 06/2000
2Ovarian Neoplasms (Ovarian Cancer)
07/2001 - 07/2000
2Leukemia
12/2000 - 04/2000
2Necrosis
12/2000 - 06/2000
1Disease Progression
01/2022
1Anaplastic Thyroid Carcinoma
01/2022
1Carcinogenesis
01/2017
1Multiple Myeloma
01/2007
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2007
1Weight Loss (Weight Reduction)
07/2006
1Acute Erythroblastic Leukemia (Erythroleukemia)
07/2006
1Medulloblastoma
01/2002
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
12/2001
1Thrombocytopenia (Thrombopenia)
12/2001
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2001
1Hypoalbuminemia
07/2001
1Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
06/2001
1Hodgkin Disease (Hodgkin's Disease)
06/2001
1Lymphoma (Lymphomas)
12/2000
1Autoimmune Diseases (Autoimmune Disease)
09/2000
1Ovarian Epithelial Carcinoma
07/2000
1Malignant Mesothelioma
07/2000
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2000
1Carcinoma (Carcinomatosis)
07/2000
1Glioblastoma (Glioblastoma Multiforme)
06/2000
1Myeloid Leukemia (Leukemia, Myelocytic)
04/2000
1Cardiomyopathies (Cardiomyopathy)
04/2000
1Diarrhea
04/2000
1Fever (Fevers)
04/2000
1B-Cell Leukemia (Leukemia, B Cell)
04/2000
1Diphtheria
04/2000
1Breast Neoplasms (Breast Cancer)
03/2000
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
03/2000

Drug/Important Bio-Agent (IBA)

11Immunotoxins (Immunotoxin)IBA
01/2017 - 02/2000
8Proteins (Proteins, Gene)FDA Link
01/2017 - 02/2000
6ExotoxinsIBA
07/2006 - 03/2000
5B3(Fv)-PE38KDEL recombinant immunotoxinIBA
12/2001 - 02/2000
3Diphtheria ToxinIBA
12/2001 - 04/2000
2Interleukin-2 (IL2)IBA
01/2002 - 12/2001
2Interleukin-4 Receptors (Interleukin 4 Receptor)IBA
01/2002 - 03/2000
2Interleukin-4 (Interleukin 4)IBA
01/2002 - 06/2000
2Recombinant ProteinsIBA
01/2002 - 04/2000
2LigandsIBA
09/2001 - 02/2000
2Transaminases (Aminotransferases)IBA
07/2001 - 04/2000
2DNA (Deoxyribonucleic Acid)IBA
06/2001 - 07/2000
2Monoclonal AntibodiesIBA
04/2000 - 04/2000
1dabrafenibIBA
01/2022
1trametinibIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
01/2017
1Bcl-2-Like Protein 11IBA
01/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
07/2006
1Messenger RNA (mRNA)IBA
01/2002
1Cytotoxins (Cytolysins)IBA
01/2002
1Interleukin-13IBA
01/2002
1denileukin diftitox (Ontak)FDA Link
12/2001
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2001
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
08/2001
1purineIBA
07/2001
1CladribineFDA LinkGeneric
07/2001
1RFB4(dsFv)-PE38 recombinant immunotoxinIBA
07/2001
1Single-Chain AntibodiesIBA
06/2001
1Complementary DNA (cDNA)IBA
06/2001
1Peptide Elongation Factor 2 (EF-2)IBA
07/2000
1Surface Antigens (Surface Antigen)IBA
07/2000
1CaspasesIBA
07/2000
1Differentiation AntigensIBA
07/2000
1MesothelinIBA
07/2000
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
07/2000
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
07/2000
1Interleukin-2 Receptor alpha SubunitIBA
07/2000
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
07/2000
1CytokinesIBA
06/2000
1GadoliniumIBA
06/2000
1InterleukinsIBA
06/2000
1interleukin-4-Pseudomonas exotoxinIBA
06/2000
1Interleukin-3 (Interleukin 3)IBA
04/2000
1Interleukin-3 Receptors (Interleukin 3 Receptor)IBA
04/2000
1AntigensIBA
04/2000
1DisulfidesIBA
04/2000
1ThymidineIBA
04/2000
1antitac(FV)-PE38 recombinant immunotoxinIBA
04/2000
1IgG Receptors (Fc gamma RI)IBA
03/2000
1Interleukin-2 Receptors (IL 2 Receptor)IBA
03/2000
1Peptides (Polypeptides)IBA
02/2000

Therapy/Procedure

7Therapeutics
01/2022 - 02/2000
2Drug Therapy (Chemotherapy)
12/2001 - 07/2001
1Catheters
06/2000
1Salvage Therapy
04/2000